Seventh age itch.

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Seventh age itch.

however, that the real value of any such trials is that they encourage standardisation of management methods, including all the items mentioned above. This conclusion might disappoint a trial technocrat, but it should be accepted as part of the difficulty and frustration inherent in clinical research. Furthermore, the scientific committees of grant giving bodies need to acknowledge more readily...

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New aspects of itch pathophysiology: component analysis of atopic itch using the 'Eppendorf Itch Questionnaire'.

Itch represents a leading symptom in dermatological practice with many psychophysiological aspects. Instruments for qualitative registration of these central nervous factors and evaluation of therapeutic measures are still missing. We analyzed in detail the subjective itch sensation in 108 patients with acute atopic eczema with a new questionnaire developed in analogy to the McGill pain questio...

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Neuropathic itch.

Chronic itch can be caused by dysfunctions of itch-sensing neurons that produce sensory hallucinations of pruritogenic stimuli. The cellular and molecular mechanisms are still unknown. All neurological disease categories have been implicated, and neurological causes should be considered for patients with otherwise-unexplained itch. The same neurological illnesses that cause neuropathic pain can...

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Enhanced itch elicited by capsaicin in a chronic itch model

Chronic itch (pruritus) is an important clinical problem. However, the underlying molecular basis has yet to be understood. The Transient Receptor Potential Vanilloid 1 channel is a heat-sensitive cation channel expressed in primary sensory neurons and involved in both thermosensation and pain, but its role in chronic itch remains elusive. Here, we for the first time revealed an increased inner...

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Nomenclatural itch versus patrolling itch: comments on O’Hara (2011)

In the last years there have been renewed criticisms towards those who, theoretically, abuse of naming new taxa, supposedly with the only (or main) objective of having their names associated to the nomina of these taxa and, thus, being ‘immortalized’ (Pillon & Chase 2007; Dubois 2008; Evenhuis 2008). As Evenhuis (2008) has carefully shown, however, this kind of criticism is almost as old as tax...

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ژورنال

عنوان ژورنال: BMJ

سال: 1985

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.291.6499.842